Intestinal permeability to polyethyleneglycol 600 in relation to macromolecular 'closure' in the neonatal pig.

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Intestinal permeability to polyethyleneglycol 600 in Crohn's disease. Peroperative determination in a defined segment of the small intestine.

Ileal permeability to different sized polyethyleneglycols (590-942 dalton PEG) was investigated peroperatively in 11 patients with Crohn's disease and seven with colonic carcinoma. A 15 cm ileal segment was converted into a tied loop, in which the PEG's were deposited. Absorption from the ileal segment was then measured as six-hour urinary recovery of the PEg dose. Polyethyleneglycol absorption...

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ژورنال

عنوان ژورنال: Gut

سال: 1984

ISSN: 0017-5749

DOI: 10.1136/gut.25.5.520